Second-Trimester Reference Intervals for Thyroid Tests: The Role of Ethnicity

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Second-trimester reference intervals for thyroid tests: the role of ethnicity.

BACKGROUND Thyroid function changes during pregnancy, complicating the diagnosis of thyroid disorders. Maternal thyroid dysfunction has been associated with a variety of adverse outcomes. We evaluated thyroid function test results by ethnicity and week of gestation during the 2nd trimester of pregnancy. METHODS We collected 3064 blood specimens in serum tubes from Asians (13%), blacks (22%), ...

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Ethnic differences in first-trimester thyroid reference intervals.

Thyroid disease is common in women of reproductive age, and the physiological changes that occur during pregnancy complicate the diagnosis of thyroid dysfunction. Trimesterand methodspecific reference intervals (RIs) for thyroid function tests (TFTs) are necessary and should be determined with thyroid autoantibody– negative individuals (1 ). Ethnic differences in TFT results exist among nonpreg...

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First- and Second-Trimester Reference Intervals for Thyroid Hormones during Pregnancy in “Rhea” Mother-Child Cohort, Crete, Greece

Estimation and interpretation of thyroid function tests in pregnant women is of utmost importance for maternal, fetal and neonatal health. Our objective was to calculate laboratory- and geography-specific reference intervals for thyroid hormones during pregnancy in an iodine-sufficient area of the Mediterranean, Crete, Greece. This project was performed in the context of "Rhea" mother-child coh...

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Effect of ethnicity on reference intervals.

The clinical chemist desiring to set up appropriate reference intervals must consider race or ethnicity as a possible factor on which to subdivide an interval. The effect of ethnicity on various analyte values has not been systematically studied (1, 2). The advent of National Health and Nutrition Examination Survey (NHANES) data (3 ) has made it possible to determine the effect of ethnicity on ...

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Establishment of Trimester-Specific Reference Intervals for Thyroid Hormones in Korean Pregnant Women

BACKGROUND Establishment of trimester- and assay-specific reference intervals for every population is recommended. The aim of this study was to establish a trimester- and assay-specific reference interval for thyroid-stimulating hormone (TSH) and free thyroxine (FT4) in Korean pregnant women. METHODS From April 2012 to December 2012, 531 pregnant women receiving prenatal care and 238 age-matc...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2007

ISSN: 0009-9147,1530-8561

DOI: 10.1373/clinchem.2007.089680